Spring. 3 credits. By arrangement with the instructor. Letter or S/U grades. Taught daily during the first 3 weeks of January.

The Biophysical Methods Advanced Laboratory Course is offered to students of the engineering, physics, chemistry and biological disciplines who are interested in research at the interface between Physical Sciences /Engineering and Life Sciences. In groups of two, participants will perform 5 experiments in research laboratories on state-of-the-art equipment. Lab training sessions are arranged individually in January and throughout the spring term. Typically each experiments will be 2 days in the lab plus one day for analysis and report writing. We are currently planning to offer experiments including fluorescence spectroscopy and mathematical modelling to study antibody binding, modern microscopy (multiphoton excitation, total internal reflection evanescent wave excitation) to study cellular function, Electron Spin Resonance studies of dynamic membrane structure, bio-electrochemistry and electrophysiology (patch clamp). The course is intended for students who seek hands-on introduction to modern biophysical experimental methods. As prerequisite the lecture course ≥Biophysical Methods≤ (A&EP 470) is highly recommended but qualified students who have not taken A&EP 470 may also be accepted.